antispyware for vista

Hi,
Up to now, I haven't bothered installing an antispyware for Vista, but now something got into my pc and it's really nasty, new IE windows open etc. Windows defender isn't (obviously) up to it, so I was wondering what I should use. BTW, I'll only get freeware, no payware. I've tried ad-aware for vista, but it's a disaster.
Any other suggestions?
Thanks.
 
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